MeSH Browser

MeSH Supplementary: 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid
Unique ID: C466644
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C466644
Entry Term(s): (1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid; TAK 475; TAK-475; TAK475; lapaquistat
Registry Numbers: 0
Heading Mapped to: *Oxazepines; *Piperidines
Frequency: 18
Note: inhibits squalene synthase; structure in first source
Source: J Med Chem 2002 Sep 26;45(20):4571-80
Indexing Information: Farnesyl-Diphosphate Farnesyltransferase
Date of Entry: 2002/10/16
Revision Date: 2008/08/01

1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid MeSH Supplementary Concept Data 2025