MeSH Browser

MeSH Supplementary: pimavanserin
Unique ID: C510793
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C510793
Entry Term(s): ACP 103; ACP-103; ACP103; N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide; Nuplazid; bis(1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)-3-(4-(2-methylpropoxy)benzyl)urea) (2R,3R)-2,3-dihydroxybutanedioate; pimavanserin tartrate; urea, n-((4-fluorophenyl)methyl)-n-(1-methyl-4-piperidinyl)-n'-((4-(2-methylpropoxy)phenyl)methyl)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
Pharm Action: Antiparkinson Agents
Antipsychotic Agents
Serotonin 5-HT2 Receptor Antagonists
Registry Numbers: JZ963P0DIK; NA83F1SJSR
Related Numbers: NA83F1SJSR
Heading Mapped to: *Piperidines; Urea / analogs & derivatives
Frequency: 155
Note: A 5-HT(2A) inverse agonist; ACP-103 is the dihydroxybutanedioate (2:1) salt. It is used to treat hallucinations and delusions associated with PARKINSON DISEASE; structure in first source.
Source: J Pharmacol Exp Ther 2006 May;317(2):910-8
Date of Entry: 2006/06/07
Revision Date: 2018/11/15

pimavanserin MeSH Supplementary Concept Data 2025