MeSH Browser

MeSH Supplementary: (2-(4-(2-benzimidazol-2ylthio)ethyl)piperazin-1yl)-N-(2,4-bis(methylthio)-6-methyl-3-pyridyl)acetamide
Unique ID: C520671
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C520671
Entry Term(s): 2-(4-(2-(benzimidazol-2- ylthio)ethyl)piperazin-1-yl)-N-(2,4- bis(methylthio)-6-methyl-3-pyridyl)acetamide; 2-(4-(2-(benzimidazol-2-ylthio)ethyl)piperazin-1-yl)-N-(2,4-bis(methylthio)-6-methyl-3-pyridyl)acetamide; K-604; K604 compound
Pharm Action: Enzyme Inhibitors
Fatty Acid Synthesis Inhibitors
Registry Number: 0
Heading Mapped to: *Benzimidazoles
Frequency: 8
Note: a selective ACAT-1 inhibitor that suppresses fatty streak lesions in fat-fed hamsters without affecting plasma cholesterol levels; structure in first source
Source: Atherosclerosis 2007 Apr;191(2):290-7
Date of Entry: 2007/06/25
Revision Date: 2018/09/24

(2-(4-(2-benzimidazol-2ylthio)ethyl)piperazin-1yl)-N-(2,4-bis(methylthio)-6-methyl-3-pyridyl)acetamide MeSH Supplementary Concept Data 2024