MeSH Browser

MeSH Supplementary: EC131 conjugate
Unique ID: C521363
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C521363
Entry Term(s): folate-maytansinoid conjugate
Registry Number: 0
Heading Mapped to: *Folic Acid; *Maytansine
Frequency: 1
Note: folate receptor-targeted drug conjugate prepared by covalently attaching the vitamin folic acid to a potent microtubule-inhibiting agent, maytansinoid DM1, via an intramolecular disulfide bond; has folate receptor-specific antitumor activity; structure in first source
Source: Cancer Res 2007 Jul 1;67(13):6376-82
Date of Entry: 2007/07/25

EC131 conjugate MeSH Supplementary Concept Data 2024