MeSH Browser

MeSH Heading: Maytansine
Tree Number(s): D02.540.505.495; D04.345.295.500
Unique ID: D008453
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008453
Scope Note: An ansa macrolide isolated from the MAYTENUS genus of East African shrubs.
Entry Term(s): DMMO-Maytansine; Emtansine; Maitansine; Maytansinoid DM1; Maytansinoid DM4; Mertansine; N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine; Ravtansine; Soravtansine
Pharm Action: Antineoplastic Agents, Phytogenic
Tubulin Modulators
Registry Number: 14083FR882
Related Numbers: 35846-53-8
Previous Indexing: Morpholines (1966-1975); Oxazines (1976)
Public MeSH Note: 91; was see under OXAZINES 1977-90
History Note: 91(77); was see under OXAZINES 1977-90
Date Established: 1991/01/01
Date of Entry: 1976/05/03
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M000626532
Registry Number: 0
Terms: Maytansinoid DM4 Preferred Term
Term UI T000915859
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (2018); N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine
Term UI T000943489
Date05/30/2018
LexicalTag NON
ThesaurusID NLM (2009); Soravtansine
Term UI T000915861
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (2018); Ravtansine
Term UI T000915860
Date02/16/2017
LexicalTag NON
ThesaurusID NLM (2018); DMMO-Maytansine
Term UI T000943488
Date05/30/2018
LexicalTag NON
ThesaurusID NLM (2009)

Maytansine MeSH Descriptor Data 2024