MeSH Browser

MeSH Supplementary: Cyclic neutropenia
Unique ID: C536227
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C536227
Entry Term(s): Cyclic Hematopoesis; Cyclic Leucopenia; Cyclic hematopoiesis; Neutropenia, cyclic; Periodic Neutropenia
Heading Mapped to: *Neutropenia
Frequency: 89
Note: A rare form of neutropenia characterized by regular 21-day cyclic fluctuations in the number of blood NEUTROPHILS; MONOCYTES; EOSINOPHILS; LYMPHOCYTES; PLATELETS, and RETICULOCYTES. Patients experience periodic symptoms of FEVER, malaise, mucosal ulcers, and, rarely, life-threatening infections. The disease occurs both as a hereditary autosomal dominant disorder and in an acquired form, with identical phenotypic presentations. Mutations in the ELANE gene have been identified for the inherited form. OMIM: 162800
Date of Entry: 2010/08/25
Revision Date: 2015/08/18

Cyclic neutropenia MeSH Supplementary Concept Data 2024