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Familial medullary thyroid carcinoma MeSH Supplementary Concept Data 2025
A malignant tumor of the CALCITONIN - secreting parafollicular C cells of the THYROID that occurs sporadically or as a component of the MULTIPLE ENDOCRINE NEOPLASIA (MEN) type 2 (OMIM: 171400)/familial medullary thyroid carcinoma (FMTC) syndromes. Germline mutations in the RET and NTRK1 genes have been identified. OMIM: 155240