MeSH Browser

MeSH Supplementary: pevonedistat
Unique ID: C539933
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C539933
Entry Term(s): ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate; ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulphamate; 4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl methyl sulfamidate; MLN-4924; MLN4924
Pharm Action: Enzyme Inhibitors
Heading Mapped to: *Cyclopentanes; *Pyrimidines
Frequency: 277
Note: a potent and selective inhibitor of NAE (NEDD8-activating enzyme)
Source: Nature. 2009 Apr 9;458(7239):732-6
Date of Entry: 2009/04/17
Revision Date: 2017/06/26

pevonedistat MeSH Supplementary Concept Data 2024