MeSH Browser

MeSH Supplementary: LGK974
Unique ID: C586458
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C586458
Entry Term(s): 2-(2',3-Dimethyl-(2,4'-bipyridin)-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide; LGK-974; WNT-974; WNT974
Pharm Action: Enzyme Inhibitors
Registry Numbers: U27F40013Q; 0
Heading Mapped to: *Pyrazines; *Pyridines
Frequency: 41
Note: a potent and specific small-molecule inhibitor of Porcupine (PORCN) acyltransferase
Source: Proc Natl Acad Sci U S A. 2013 Dec 10;110(50);20224-9
Date of Entry: 2014/02/19
Revision Date: 2018/05/11

LGK974 MeSH Supplementary Concept Data 2025