MeSH Browser

MeSH Heading: RNA Recognition Motif
Tree Number(s): G02.111.570.820.709.275.500.869.500
Unique ID: D000071377
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071377
Scope Note: An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.
Entry Term(s): RRM Motif; Ribonucleoprotein Domain
Previous Indexing: Amino Acid Sequence (1989-2016); RNA-Binding Proteins (1991-2016)
See Also: RNA Recognition Motif Proteins
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/05/12

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M000613902
Scope Note: An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.
Terms: RNA Recognition Motif Preferred Term
Term UI T000894279
Date01/27/2016
LexicalTag ABX
ThesaurusID NLM (2017); RRM Motif
Term UI T000894280
Date01/27/2016
LexicalTag ABX
ThesaurusID NLM (2017); Ribonucleoprotein Domain
Term UI T000894282
Date01/27/2016
LexicalTag NON
ThesaurusID NLM (2017)

RNA Recognition Motif MeSH Descriptor Data 2024