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Clonal Hematopoiesis MeSH Descriptor Data 2022


MeSH Heading
Clonal Hematopoiesis
Tree Number(s)
G04.152.825.207
G04.375.500
G05.158.500
G09.188.343.207
Unique ID
D000082182
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000082182
Scope Note
Expansion of blood cells arising from mutant HEMATOPOIETIC STEM CELLS often related to aging. Mutations on epigenetic regulator genes are common in clonal hematopoiesis and may be a risk factor for HEMATOLOGIC NEOPLASMS and other cardiovascular diseases. When variant allele fraction is at least 2% and is present in the absence of severe cytopenias it is referred to as clonal hematopoiesis of indeterminate potential (CHIP).
Entry Term(s)
ARCH Age-related Clonal Hematopoiesis
Age-related Clonal Hematopoiesis
CCUS Clonal Cytopenia of Undetermined Significance
CHIP Clonal Hematopoiesis of Indeterminate Potential
Clonal Cytopenia of Undetermined Significance
Clonal Hematopoiesis of Indeterminate Potential
ICUS Idiopathic Cytopenias of Undetermined Significance
Idiopathic Cytopenias of Undetermined Significance
Previous Indexing
Hematopoiesis (1989-2020)
Public MeSH Note
2021
History Note
2021
Date Established
2021/01/01
Date of Entry
2020/07/07
Revision Date
2020/05/27
Clonal Hematopoiesis Preferred
Age-related Clonal Hematopoiesis Narrower
CHIP Clonal Hematopoiesis of Indeterminate Potential Narrower
Idiopathic Cytopenias of Undetermined Significance Narrower
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