Genetic Risk Score MeSH Descriptor Data 2024

MeSH Heading: Genetic Risk Score
Tree Number(s): C23.550.291.687.500.750; E05.318.740.600.800.725.250; G05.380.355.500; N05.715.360.750.625.700.700.250; N06.850.520.830.600.800.725.250
Unique ID: D000096442
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000096442
Scope Note: Estimate of an individual's genetic liability to a trait or disease, calculated according to their genotype profile and relevant genome-wide association study data. (from Tutorial: a guide to performing polygenic risk score analyses. Nat Protoc. 2020 Sep;15(9):2759.)
Entry Term(s): Polygenic Risk Score
Previous Indexing: Genetic Predisposition to Disease (1999-2023)
Public MeSH Note: 2024
History Note: 2024
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/14

Allowable Qualifiers: classification (CL)

epidemiology (EP)

ethnology (EH)

Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
  - Disease Attributes [C23.550.291]
    - Disease Susceptibility [C23.550.291.687]
      - Genetic Predisposition to Disease [C23.550.291.687.500]
        
        Anticipation, Genetic [C23.550.291.687.500.500]
        
        Genetic Risk Score [C23.550.291.687.500.750]

Investigative Techniques [E05]
- Epidemiologic Methods [E05.318]
  - Statistics as Topic [E05.318.740]
    - Probability [E05.318.740.600]
      - Risk [E05.318.740.600.800]
        
        Risk Factors [E05.318.740.600.800.725]
        
        Genetic Risk Score [E05.318.740.600.800.725.250]
        
        Heart Disease Risk Factors [E05.318.740.600.800.725.500]

Genetic Phenomena [G05]
- Genotype [G05.380]
  - Genetic Predisposition to Disease [G05.380.355]
    - Genetic Risk Score [G05.380.355.500]

Health Care Quality, Access, and Evaluation [N05]
- Quality of Health Care [N05.715]
  - Health Care Evaluation Mechanisms [N05.715.360]
    - Statistics as Topic [N05.715.360.750]
      - Probability [N05.715.360.750.625]
        
        Risk [N05.715.360.750.625.700]
        
        Risk Factors [N05.715.360.750.625.700.700]
        
        Genetic Risk Score [N05.715.360.750.625.700.700.250]
        
        Heart Disease Risk Factors [N05.715.360.750.625.700.700.500]

Environment and Public Health [N06]
- Public Health [N06.850]
  - Epidemiologic Methods [N06.850.520]
    - Statistics as Topic [N06.850.520.830]
      - Probability [N06.850.520.830.600]
        
        Risk [N06.850.520.830.600.800]
        
        Risk Factors [N06.850.520.830.600.800.725]
        
        Genetic Risk Score [N06.850.520.830.600.800.725.250]
        
        Heart Disease Risk Factors [N06.850.520.830.600.800.725.500]

Genetic Risk Score Preferred

Polygenic Risk Score Narrower

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