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Complement Fixation Tests MeSH Descriptor Data 2025
Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.
Entry Term(s)
Complement Absorption Test, Conglutinating
Conglutinating Complement Absorption Test
Conglutination Reaction
NLM Classification #
QY 265
Public MeSH Note
CONGLUTINATION REACTION was heading 1975-96 (see under COMPLEMENT FIXATION TESTS 1975-90); COMPLEMENT ABSORPTION TEST, CONGLUTINATING was see CONGLUTINATION REACTION 1992-96
History Note
CONGLUTINATION REACTION was heading 1975-96 (see under COMPLEMENT FIXATION TESTS 1975-90); COMPLEMENT ABSORPTION TEST, CONGLUTINATING was see CONGLUTINATION REACTION 1992-96
Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.