MeSH Browser

MeSH Heading: Coombs Test
Tree Number(s): E01.370.225.812.735.050.375.150; E05.200.812.735.050.375.150; E05.478.594.760.050.375.150
Unique ID: D003298
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003298
Annotation: for erythrocytes only: for lymphocytes consider HISTOCOMPATIBILITY TESTING or CYTOTOXICITY TESTS, IMMUNOLOGIC
Scope Note: A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.
Entry Term(s): Anti-Human Globulin Consumption Test; Antiglobulin Consumption Test; Antiglobulin Test; Antihuman Globulin Consumption Test; Coombs' Test; Direct Antiglobulin Test; Direct Coombs Test; Indirect Antiglobulin Test; Indirect Coombs Test
Public MeSH Note: 2013; see COOMBS' TEST 1966-2012
History Note: 2013 (1966)
Date Established: 2013/01/01
Date of Entry: 1999/01/01
Revision Date: 2012/07/03

Allowable Qualifiers: classification (CL)

economics (EC)

ethics (ES)

history (HI)

instrumentation (IS)

methods (MT)

standards (ST)

statistics & numerical data (SN)

trends (TD)

veterinary (VE)

Concept UI: M0005148
Scope Note: A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.
Terms: Coombs Test Preferred Term
Term UI T821564
Date04/30/2012
LexicalTag EPO
ThesaurusID NLM (2013); Antiglobulin Test
Term UI T009654
Date03/29/1974
LexicalTag NON
ThesaurusID UNK (19XX); Antiglobulin Consumption Test
Term UI T009653
Date01/01/1975
LexicalTag NON
ThesaurusID UNK (19XX); Antihuman Globulin Consumption Test
Term UI T009656
Date10/15/1990
LexicalTag NON
ThesaurusID NLM (1992); Coombs' Test
Term UI T009655
Date01/01/1999
LexicalTag EPO
ThesaurusID NLM (1966)

Coombs Test MeSH Descriptor Data 2024