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Genes, Homeobox MeSH Descriptor Data 2025


MeSH Heading
Genes, Homeobox
Tree Number(s)
G05.360.340.024.340.230.500
Unique ID
D005801
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005801
Scope Note
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
Entry Term(s)
Genes, Homeo Box
Genes, Homeotic
Homeo Box
Homeo Box Sequence
Homeo Boxes
Homeobox
Homeobox Sequence
Homeoboxes
Homeotic Genes
Hox Genes
Sequence, Homeo Box
NLM Classification #
QU 470
Previous Indexing
Alleles (1968-1975)
Drosophila Melanogaster (1972-1986)
Genes, Structural (1983-1986)
Morphogenesis (1983-1986)
See Also
Homeodomain Proteins
Public MeSH Note
95; was GENES, HOMEO BOX 1987-94
Online Note
use GENES, HOMEOBOX to search GENES, HOMEO BOX 1987-94
History Note
95; was GENES, HOMEO BOX 1987-94
Date Established
1987/01/01
Date of Entry
1986/06/18
Revision Date
2012/07/03
Genes, Homeobox Preferred
Homeo Box Sequence Narrower
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