Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Intervertebral Disc Chemolysis MeSH Descriptor Data 2025


MeSH Heading
Intervertebral Disc Chemolysis
Tree Number(s)
E02.718.500
Unique ID
D007404
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007404
Annotation
coordinate IM with specific substance /‌ther use (usually CHYMOPAPAIN) if particularly discussed
Scope Note
The dissolving of the NUCLEUS PULPOSUS, the semi-gelatinous tissue of a displaced INTERVERTEBRAL DISC. It is usually achieved by the direct injection of a proteolytic enzyme, especially CHYMOPAPAIN, into the herniated disc.
Entry Term(s)
Chemolysis, Intervertebral Disc
Chemolysis, Intervertebral Disk
Chemonucleolysis
Discolysis
Intervertebral Disk Chemolysis
Nucleolysis, Intervertebral Disc
Nucleolysis, Intervertebral Disk
NLM Classification #
WE 740
Previous Indexing
Chymopapain (1975-1986)
Intervertebral Disk Displacement (1966-1986)
See Also
Chymopapain
Public MeSH Note
2012; see INTERVERTEBRAL DISK CHEMOLYSIS 1987-2011
History Note
2012 (1987)
Date Established
1987/01/01
Date of Entry
1986/06/20
Revision Date
2016/01/20
Intervertebral Disc Chemolysis Preferred
page delivered in 0.126s