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Lymphocyte Culture Test, Mixed MeSH Descriptor Data 2022


MeSH Heading
Lymphocyte Culture Test, Mixed
Tree Number(s)
E01.370.225.812.385.475
E05.200.812.385.475
E05.478.594.385.429
Unique ID
D007959
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007959
Annotation
NIM
Scope Note
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
Entry Term(s)
Leukocyte Culture Test, Mixed
Mixed Leukocyte Culture Test
Mixed Leukocyte Reaction
Mixed Lymphocyte Culture Test
Mixed Lymphocyte Reaction
Previous Indexing
Histocompatibility Testing (1968-1972)
Leukocytes (1966-1972)
Public MeSH Note
93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92
Online Note
use LYMPHOCYTE CULTURE TEST, MIXED to search LEUKOCYTE CULTURE TEST, MIXED 1973-92
History Note
93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2011/06/24
Lymphocyte Culture Test, Mixed Preferred
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