MeSH Browser

MeSH Heading: Synaptic Transmission
Tree Number(s): G02.111.820.850; G04.835.850; G07.265.880; G11.561.830
Unique ID: D009435
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009435
Annotation: differentiate entry term NEURAL TRANSMISSION from NEURAL CONDUCTION; consider also NEURAL INHIBITION; neuromuscular transmission = NEUROMUSCULAR JUNCTION / physiol + SYNAPTIC TRANSMISSION
Scope Note: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Entry Version: SYNAPTIC TRANSM
Entry Term(s): Neural Transmission; Neurotransmission; Transmission, Neural; Transmission, Synaptic
Previous Indexing: Neural Conduction (1966-1967)
See Also: Gap Junctions; Synapses
Public MeSH Note: 94; was NEURAL TRANSMISSION 1969-93, was NEUROHUMORAL TRANSMISSION 1968; NERVE TRANSMISSION was see NEURAL TRANSMISSION
Online Note: use SYNAPTIC TRANSMISSION to search NEURAL TRANSMISSION 1969-93, NEUROHUMORAL TRANSMISSION 1968, & NERVE TRANSMISSION 1968-93
History Note: 94; was NEURAL TRANSMISSION 1969-93, was NEUROHUMORAL TRANSMISSION 1968; NERVE TRANSMISSION was see NEURAL TRANSMISSION 1969-93
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/23

Concept UI: M0014683
Scope Note: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Terms: Synaptic Transmission Preferred Term
Term UI T028124
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1968); Transmission, Neural
Term UI T028121
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Neural Transmission
Term UI T028122
Date01/21/1993
LexicalTag NON
ThesaurusID NLM (1994); Transmission, Synaptic
Term UI T028123
Date01/21/1993
LexicalTag NON
ThesaurusID NLM (1994); Neurotransmission
Term UI T712497
Date01/09/2008
LexicalTag NON
ThesaurusID NLM (2009)

Synaptic Transmission MeSH Descriptor Data 2024