MeSH Browser

MeSH Heading: Loss of Heterozygosity
Tree Number(s): G05.365.590.029.530
Unique ID: D019656
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019656
Annotation: do not confuse entry term ALLELIC LOSS with ALLELIC IMBALANCE
Scope Note: The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.
Entry Term(s): Allelic Loss; Heterozygosity, Loss of
Previous Indexing: Chromosome Deletion (1987-1997); Heterozygote (1983-1997)
See Also: Hemizygote
Public MeSH Note: 98
History Note: 98
Date Established: 1998/01/01
Date of Entry: 1997/07/14
Revision Date: 2010/06/25

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Loss of Heterozygosity MeSH Descriptor Data 2024