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Loss of Heterozygosity MeSH Descriptor Data 2022


MeSH Heading
Loss of Heterozygosity
Tree Number(s)
G05.365.590.029.530
Unique ID
D019656
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019656
Annotation
do not confuse entry term ALLELIC LOSS with ALLELIC IMBALANCE
Scope Note
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.
Entry Term(s)
Allelic Loss
Heterozygosity, Loss of
Previous Indexing
Chromosome Deletion (1987-1997)
Heterozygote (1983-1997)
See Also
Hemizygote
Public MeSH Note
98
History Note
98
Date Established
1998/01/01
Date of Entry
1997/07/14
Revision Date
2010/06/25
Loss of Heterozygosity Preferred
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