NLM Logo

Inhibitory Concentration 50 MeSH Descriptor Data 2022


MeSH Heading
Inhibitory Concentration 50
Tree Number(s)
E05.940.350
G07.690.936.563
Unique ID
D020128
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020128
Annotation
do not confuse with LETHAL DOSE 50, determined in animals
Scope Note
The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.
Entry Term(s)
IC50
Previous Indexing
Cell Survival/drug effects (1971-1998)
See Also
Microbial Sensitivity Tests
Public MeSH Note
99
History Note
99
Date Established
1999/01/01
Date of Entry
1998/06/10
Revision Date
2016/06/28

No Qualifiers
Inhibitory Concentration 50 Preferred
page delivered in 0.134s