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E-Box Elements MeSH Descriptor Data 2022


MeSH Heading
E-Box Elements
Tree Number(s)
G02.111.570.080.689.330.240
G05.360.080.689.330.240
G05.360.340.024.340.137.750.249.240
Unique ID
D024721
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D024721
Scope Note
DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
Entry Term(s)
E-Box Motifs
E-Box Sequences
E-Box Sites
Public MeSH Note
2002
History Note
2002
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2009/07/14
E-Box Elements Preferred
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