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Clinical Trials Data Monitoring Committees MeSH Descriptor Data 2023


MeSH Heading
Clinical Trials Data Monitoring Committees
Tree Number(s)
N05.700.685.149
Unique ID
D026661
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D026661
Scope Note
Committees established to review interim data and efficacy outcomes in clinical trials. The findings of these committees are used in deciding whether a trial should be continued as designed, changed, or terminated. Government regulations regarding federally-funded research involving human subjects (the "Common Rule") require (45 CFR 46.111) that research ethics committees reviewing large-scale clinical trials monitor the data collected using a mechanism such as a data monitoring committee. FDA regulations (21 CFR 50.24) require that such committees be established to monitor studies conducted in emergency settings.
Entry Version
CLIN TRIALS DATA MONITORING COMMITTEES
Entry Term(s)
Data Monitoring Committees
Data and Safety Monitoring Boards
Safety Monitoring Boards
Previous Indexing
Clinical Trials (1991-2001)
Professional Staff Committees (1991-2001)
See Also
Clinical Trials as Topic
Ethics Committees, Research
Research Design
Public MeSH Note
2002
History Note
2002
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2009/07/15
Clinical Trials Data Monitoring Committees Preferred
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