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Leukocyte Rolling MeSH Descriptor Data 2022


MeSH Heading
Leukocyte Rolling
Tree Number(s)
G04.198.424.233.500
Unique ID
D036904
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D036904
Scope Note
Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)
Entry Term(s)
Leucocyte Rolling
Previous Indexing
Cell Adhesion (1991-2002)
Cell Movement (1991-2002)
Public MeSH Note
2003
History Note
2003
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2016/06/23
Leukocyte Rolling Preferred
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