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Matrix Attachment Regions MeSH Descriptor Data 2025


MeSH Heading
Matrix Attachment Regions
Tree Number(s)
G02.111.570.080.534
G05.360.080.534
Unique ID
D045170
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D045170
Scope Note
Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.
Entry Term(s)
MAR Elements
MAR-SAR Recognition Signature Sequence
MRS Sequence
Matrix-Attached Regions
SAR Elements
Scaffold Attachment Regions
Scaffold-Attached Regions
Previous Indexing
Nuclear Matrix/metabolism (1990-2003)
Public MeSH Note
2004
History Note
2004
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2011/12/12
Matrix Attachment Regions Preferred
MRS Sequence Narrower
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