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Endodermal Sinus Tumor MeSH Descriptor Data 2025


MeSH Heading
Endodermal Sinus Tumor
Tree Number(s)
C04.557.465.510.350
Unique ID
D018240
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018240
Annotation
coordinate with precoordinated organ/neoplasm term
Scope Note
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
Entry Term(s)
Yolk Sac Tumor
Previous Indexing
Mesonephroma (1968-1993)
Public MeSH Note
94; was see MESONEPHROMA 1979-93; YOLK SAC TUMOR was see MESONEPHROMA 1979-93
Online Note
use MESONEPHROMA to search ENDODERMAL SINUS TUMOR & YOLK SAC TUMOR 1979-93
History Note
94; was see MESONEPHROMA 1979-93; YOLK SAC TUMOR was see MESONEPHROMA 1979-93
Date Established
1994/01/01
Date of Entry
1993/06/25
Revision Date
2009/07/06
Endodermal Sinus Tumor Preferred
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