MeSH Browser

MeSH Heading: Receptors, GABA
Tree Number(s): D12.776.543.750.720.200.300
Unique ID: D018079
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018079
Scope Note: Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Entry Version: RECEPT GABA
Entry Term(s): GABA Receptor; GABA Receptors; Receptors, gamma-Aminobutyric Acid; gamma-Aminobutyric Acid Receptor; gamma-Aminobutyric Acid Receptors
NLM Classification #: QU 60
Previous Indexing: GABA (1979-1984); Receptors, Cell Surface (1973-1984); Receptors, GABA-A (1985-1993)
See Also: GABA Plasma Membrane Transport Proteins
Public MeSH Note: 94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93
Online Note: use RECEPTORS, GABA-A to search GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID 1985-93
History Note: 94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93
Entry Combination: agonists:GABA Agonists; antagonists & inhibitors:GABA Antagonists
Date Established: 1994/01/01
Date of Entry: 1993/06/21
Revision Date: 2005/06/30

Entry Combination: agonists:GABA Agonists; antagonists & inhibitors:GABA Antagonists
Allowable Qualifiers: administration & dosage (AD)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Amino Acid [D12.776.543.750.720.200]
        
        Receptors, GABA [D12.776.543.750.720.200.300]
        
        Receptors, GABA-A [D12.776.543.750.720.200.300.300]
        
        Receptors, GABA-B [D12.776.543.750.720.200.300.320]
        
        Receptors, Glutamate [D12.776.543.750.720.200.450]
        
        Receptors, Glycine [D12.776.543.750.720.200.470]

Receptors, GABA Preferred

Concept UI: M0027273
Scope Note: Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Terms: Receptors, GABA Preferred Term
Term UI T054100
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1994); GABA Receptors
Term UI T054099
Date02/01/1993
LexicalTag NON
ThesaurusID NLM (1994); gamma-Aminobutyric Acid Receptor
Term UI T054095
Date02/01/1993
LexicalTag NON
ThesaurusID NLM (1994); gamma-Aminobutyric Acid Receptors
Term UI T054096
Date02/22/1993
LexicalTag NON
ThesaurusID NLM (1994); Receptors, gamma-Aminobutyric Acid
Term UI T054097
Date02/01/1993
LexicalTag NON
ThesaurusID NLM (1994); GABA Receptor
Term UI T054098
Date02/22/1993
LexicalTag NON
ThesaurusID NLM (1994)

Receptors, GABA MeSH Descriptor Data 2024