MeSH Browser

MeSH Heading: G(M2) Ganglioside
Tree Number(s): D09.400.410.420.025.475.400; D10.390.470.025.475.400; D10.570.877.360.025.475.400
Unique ID: D005678
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005678
Scope Note: A glycosphingolipid that accumulates due to a deficiency of hexosaminidase A or B (BETA-N-ACETYLHEXOSAMINIDASES), or GM2 activator protein, resulting in GANGLIOSIDOSES, heredity metabolic disorders that include TAY-SACHS DISEASE and SANDHOFF DISEASE.
Entry Version: GM2 GANGLIOSIDE
Entry Term(s): GM2 Ganglioside; Ganglioside GM2; Tay-Sachs Disease Ganglioside
CAS Type 1 Name: Ganglioside GM2
Previous Indexing: Gangliosides (1974)
See Also: Sandhoff Disease; Tay-Sachs Disease
Public MeSH Note: 91; was see under GANGLIOSIDES 1975-90
History Note: 91(75); was see under GANGLIOSIDES 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2019/03/22

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0008925
Scope Note: A glycosphingolipid that accumulates due to a deficiency of hexosaminidase A or B (BETA-N-ACETYLHEXOSAMINIDASES), or GM2 activator protein, resulting in GANGLIOSIDOSES, heredity metabolic disorders that include TAY-SACHS DISEASE and SANDHOFF DISEASE.
Terms: G(M2) Ganglioside Preferred Term
Term UI T017174
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); GM2 Ganglioside
Term UI T000952288
Date02/28/2019
LexicalTag NON
ThesaurusID NLM (2020); Tay-Sachs Disease Ganglioside
Term UI T017175
Date05/20/1976
LexicalTag EPO
ThesaurusID UNK (19XX); Ganglioside GM2
Term UI T017176
Date04/23/1988
LexicalTag NON
ThesaurusID UNK (19XX)

G(M2) Ganglioside MeSH Descriptor Data 2024