MeSH Browser

MeSH Heading: Glucagon-Like Peptide 1
Tree Number(s): D06.472.317.680.500.500
Unique ID: D052216
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D052216
Scope Note: A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
Entry Term(s): GLP-1; Glucagon-Like Peptide-1
Pharm Action: Incretins
Public MeSH Note: 2006
History Note: 2006
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2018/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0160181
Scope Note: A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
Terms: Glucagon-Like Peptide 1 Preferred Term
Term UI T190186
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); GLP-1
Term UI T190181
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Glucagon-Like Peptide-1
Term UI T190182
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Glucagon-Like Peptide 1 MeSH Descriptor Data 2024