- Concept UI
- M0011417
- Registry Numbers
- 0
- Scope Note
- A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
- Terms
-
Insulin
Preferred Term
Term UI
T021939
Date01/01/1999
LexicalTag
NON
ThesaurusID
-
Insulin, Regular
Term UI
T493682
Date05/14/2002
LexicalTag
NON
ThesaurusID
NLM (2003)
-
Soluble Insulin
Term UI
T790029
Date05/02/2011
LexicalTag
NON
ThesaurusID
NLM (2012)