- Concept UI
- M0014953
- Scope Note
- A blood protein (NSILA) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of Cohn fraction III, 10% of the activity is found in the supernatant (NSILA-S) and the remaining activity in the precipitate (NSILA-P). The latter is a large molecular compound, much less stable than the soluble fraction. NSILA-S is a more potent growth factor than insulin and exhibits sulfation activity.
- Terms
-
Nonsuppressible Insulin-Like Activity
Preferred Term
Term UI
T028653
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1977)
-
NSILA
Term UI
T028654
Date05/12/1976
LexicalTag
ABB
ThesaurusID
UNK (19XX)
-
Nonsuppressible Insulinlike Activity
Term UI
T028655
Date12/07/1977
LexicalTag
NON
ThesaurusID
UNK (19XX)