MeSH Browser

MeSH Heading: Somatomedins
Tree Number(s): D12.644.276.742.500; D12.776.124.862; D23.529.742.500
Unique ID: D013002
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013002
Scope Note: Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They regulate cell growth through interaction with SOMATOMEDIN RECEPTORS.
Entry Term(s): NSILA; NSILA-P; NSILA-S; Nonsuppressible Insulin-Like Activity; Nonsuppressible Insulinlike Activity; Somatomedin; Sulfation Factor
Registry Numbers: 0
NLM Classification #: QU 107
Previous Indexing: Blood Proteins (1966-1970); Sulfates/metabolism (1966-1970)
See Also: Receptors, Somatomedin
Public MeSH Note: 1982; was SOMATOMEDIN 1973-1981
Online Note: use SOMATOMEDINS to search SOMATOMEDIN 1973-81 & SULFATION FACTOR 1971-72 (as Prov 1971-72)
History Note: 1982; was SOMATOMEDIN 1973-1981, was SULFATION FACTOR 1971-1972 (Prov)
Date Introduced: 1973/01/01
Last Updated: 2026/01/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Somatomedins MeSH Descriptor Data 2026