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Insulin-Like Growth Factor II MeSH Descriptor Data 2024

MeSH Heading
Insulin-Like Growth Factor II
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
Entry Term(s)
Insulin Like Growth Factor II
Insulin-Like Somatomedin Peptide II
Multiplication-Stimulating Activity
Multiplication-Stimulating Factor
Somatomedin A
Somatomedin MSA
Related Numbers
CAS Type 1 Name
Insulin-like growth factor II
NLM Classification #
QU 107
Previous Indexing
Blood Proteins (1966-1985)
Growth Substances (1966-1985)
Insulin (1966-1985)
Peptides (1966-1985)
Somatomedins (1973-1985)
Sulfation Factor (1971-1972)
See Also
Receptor, IGF Type 1
Receptor, IGF Type 2
Public MeSH Note
1991; see SOMATOMEDINS 1986-1990; SOMATOMEDIN A was indexed under INSULIN-LIKE GROWTH FACTOR II 1980-2004
History Note
Date Established
Date of Entry
Revision Date
Insulin-Like Growth Factor II Preferred
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