MeSH Browser

MeSH Heading: Insulin-Like Growth Factor I
Tree Number(s): D12.776.124.862.400
Unique ID: D007334
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007334
Scope Note: A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
Entry Term(s): IGF-1; IGF-I; IGF-I-SmC; Insulin Like Growth Factor I; Insulin-Like Somatomedin Peptide I; Somatomedin C
CAS Type 1 Name: Insulin-like growth factor I
NLM Classification #: QU 107
Previous Indexing: Growth Substances (1966-1985); Insulin (1966-1985); Peptides (1966-1985); Somatomedins (1973-1985); Sulfation Factor (1971-1972)
See Also: Receptor, IGF Type 1
Public MeSH Note: 91; was see under SOMATOMEDINS 1986-90
History Note: 91(86); was see under SOMATOMEDINS 1986-90
Date Established: 1991/01/01
Date of Entry: 1985/04/25
Revision Date: 2023/05/17

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0011434
Scope Note: A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
Terms: Insulin-Like Growth Factor I Preferred Term
Term UI T021963
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1986); IGF-1
Term UI T021960
Date04/25/1985
LexicalTag ABB
ThesaurusID UNK (19XX); IGF-I-SmC
Term UI T021961
Date04/25/1985
LexicalTag ABB
ThesaurusID UNK (19XX); IGF-I
Term UI T021959
Date04/25/1985
LexicalTag ABB
ThesaurusID UNK (19XX); Insulin-Like Somatomedin Peptide I
Term UI T021964
Date04/25/1985
LexicalTag NON
ThesaurusID UNK (19XX); Somatomedin C
Term UI T021965
Date04/25/1985
LexicalTag NON
ThesaurusID UNK (19XX); Insulin Like Growth Factor I
Term UI T021962
Date04/25/1985
LexicalTag NON
ThesaurusID UNK (19XX)

Insulin-Like Growth Factor I MeSH Descriptor Data 2024