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Receptors, LDL MeSH Descriptor Data 2025


MeSH Heading
Receptors, LDL
Tree Number(s)
D12.776.543.750.710.450
Unique ID
D011973
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011973
Scope Note
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.
Entry Version
RECEPT LDL
Entry Term(s)
LDL Receptor
LDL Receptors
LDL Receptors, Lipoprotein
Lipoprotein LDL Receptors
Low Density Lipoprotein Receptor
Low Density Lipoprotein Receptors
Receptors, Lipoprotein, LDL
Receptors, Low Density Lipoprotein
Registry Numbers
0
NLM Classification #
QU 95
Previous Indexing
Lipoproteins, LDL (1972-1984)
Receptors, Endogenous Substances (1973-1984)
See Also
Lipoproteins, LDL
Public MeSH Note
85; LIPOPROTEINS, LDL RECEPTORS was see RECEPTORS, LDL 1985-92
Online Note
use RECEPTORS, LDL to search LIPOPROTEINS, LDL RECEPTORS 1985-92
History Note
85; LIPOPROTEINS, LDL RECEPTORS was see RECEPTORS, LDL 1985-92
Date Established
1985/01/01
Date of Entry
1984/05/25
Revision Date
2006/07/05
Receptors, LDL Preferred
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