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Enkephalin, Methionine MeSH Descriptor Data 2025


MeSH Heading
Enkephalin, Methionine
Tree Number(s)
D12.644.400.575.281.381
D12.776.631.650.575.281.381
Unique ID
D004744
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004744
Scope Note
One of the endogenous pentapeptides with morphine-like activity. It differs from LEU-ENKEPHALIN by the amino acid METHIONINE in position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.
Entry Version
ENKEPHALIN MET
Entry Term(s)
5-Methionine Enkephalin
Met(5)-Enkephalin
Met-Enkephalin
Methionine Enkephalin
Pharm Action
Neurotransmitter Agents
Registry Numbers
58569-55-4
CAS Type 1 Name
Tyr-Gly-Gly-Phe-Met
Previous Indexing
Enkephalins (Aug 1977-1982)
Nerve Tissue Proteins (1966-Jul 1977)
Peptides (1966-Jul 1977)
Public MeSH Note
83
History Note
83
Date Established
1983/01/01
Date of Entry
1982/05/04
Revision Date
2015/11/23
Enkephalin, Methionine Preferred
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