MeSH Browser

MeSH Heading: Enkephalin, Leucine
Tree Number(s): D12.644.400.575.281.231; D12.776.631.650.575.281.231
Unique ID: D004743
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004743
Scope Note: One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.
Entry Version: ENKEPHALIN LEU
Entry Term(s): 5-Leucine Enkephalin; Leu(5)-Enkephalin; Leu-Enkephalin; Leucine Enkephalin
Pharm Action: Neurotransmitter Agents
CAS Type 1 Name: Tyr-Gly-Gly-Phe-Leu
Previous Indexing: Enkephalins (Aug 1977-1982); Nerve Tissue Proteins (1966-Jul 1977); Peptides (1966-Jul 1977)
Public MeSH Note: 83
History Note: 83
Date Established: 1983/01/01
Date of Entry: 1982/05/04
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0007454
Scope Note: One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.
Terms: Enkephalin, Leucine Preferred Term
Term UI T014494
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1983); Leu-Enkephalin
Term UI T014492
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX); Leucine Enkephalin
Term UI T014493
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX); Leu(5)-Enkephalin
Term UI T014495
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX); 5-Leucine Enkephalin
Term UI T014496
Date05/04/1982
LexicalTag NON
ThesaurusID UNK (19XX)

Enkephalin, Leucine MeSH Descriptor Data 2024