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Monoamine Oxidase MeSH Descriptor Data 2022


MeSH Heading
Monoamine Oxidase
Tree Number(s)
D08.811.682.664.750
Unique ID
D008995
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008995
Scope Note
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
Entry Term(s)
Amine Oxidase (Flavin-Containing)
MAO
MAO-A
MAO-B
Monoamine Oxidase A
Monoamine Oxidase B
Type A Monoamine Oxidase
Type B Monoamine Oxidase
Tyramine Oxidase
Registry Number
EC 1.4.3.4
Related Numbers
9001-66-5
CAS Type 1 Name
Amine:oxygen oxidoreductase (deaminating) (flavin-containing)
NLM Classification #
QU 140
Public MeSH Note
63; TYRAMINE OXIDASE was indexed under AMINE OXIDOREDUCTASES 1980-98
History Note
63; for TYRAMINE OXIDASE use MONOAMINE OXIDASE (NM) 1980-98
Entry Combination
antagonists & inhibitors:Monoamine Oxidase Inhibitors
Date Established
1963/01/01
Date of Entry
1999/01/01
Revision Date
2005/06/30
Monoamine Oxidase Preferred
Type A Monoamine Oxidase Narrower
Monoamine Oxidase B Narrower
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