MeSH Browser

MeSH Heading: Phencyclidine
Tree Number(s): D03.383.621.699
Unique ID: D010622
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010622
Scope Note: A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.
Entry Term(s): 1-(1-Phenylcyclohexyl)piperidine; Angel Dust; CL-395; GP-121; Phencyclidine Hydrobromide; Phencyclidine Hydrochloride; Sernyl; Serylan
Pharm Action: Enzyme Inhibitors
Hallucinogens
Excitatory Amino Acid Antagonists
Related Numbers: 2981-31-9; 77-10-1; 956-90-1; V1JZQ7GDTX
CAS Type 1 Name: Piperidine, 1-(1-phenylcyclohexyl)-
NLM Classification #: QV 77.7
Previous Indexing: Anesthetics (1966-1972); Piperidines (1968-1972)
See Also: Phencyclidine Abuse; Receptors, Phencyclidine
Public MeSH Note: 73; was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967.
History Note: 73(64); was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0016495
Related Numbers: 2981-31-9; 77-10-1; 956-90-1; V1JZQ7GDTX
Scope Note: A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.
Terms: Phencyclidine Preferred Term
Term UI T031352
Date01/01/1999
LexicalTag NON
ThesaurusID; 1-(1-Phenylcyclohexyl)piperidine
Term UI T031349
Date12/03/1986
LexicalTag NON
ThesaurusID UNK (19XX); Angel Dust
Term UI T031350
Date04/01/1992
LexicalTag NON
ThesaurusID NLM (1993)

Phencyclidine MeSH Descriptor Data 2024