MeSH Browser

MeSH Heading: Selegiline
Tree Number(s): D02.092.471.683.915
Unique ID: D012642
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012642
Scope Note: A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.
Entry Term(s): Deprenalin; Deprenil; Deprenyl; E-250; Eldepryl; Emsam; Humex; Jumex; L-Deprenyl; Selegiline Hydrochloride; Selegiline Hydrochloride, (R)-Isomer; Selegiline Hydrochloride, (R,S)-Isomer; Selegiline Hydrochloride, (S)-Isomer; Selegiline, (R)-Isomer; Selegiline, (R,S)-Isomer; Selegiline, (S)-Isomer; Selegyline; Yumex; Zelapar
Pharm Action: Antidepressive Agents
Antiparkinson Agents
Monoamine Oxidase Inhibitors
Neuroprotective Agents
Related Numbers: 1205-70-5; 14611-51-9; 14611-52-0; 2079-54-1; 2323-36-6; 4528-51-2; 4528-52-3; 4530-70-5; 6W731X367Q
CAS Type 1 Name: Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, (R)-
Previous Indexing: Monoamine Oxidase Inhibitors (1966-1978); Phenethylamines (1966-1978)
Public MeSH Note: 91; was see under PHENETHYLAMINES 1984-90; was DEPRENYL see under PHENETHYLAMINES 1979-83
Online Note: use SELEGILINE to search DEPRENYL 1979-83
History Note: 91(84); was see under PHENETHYLAMINES 1984-90; was DEPRENYL see under PHENETHYLAMINES 1979-83
Date Established: 1991/01/01
Date of Entry: 1977/12/09
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Amines [D02.092]
  - Ethylamines [D02.092.471]
    - Phenethylamines [D02.092.471.683]

Selegiline Preferred

Concept UI: M0019601
Related Numbers: 1205-70-5; 14611-51-9; 14611-52-0; 2079-54-1; 2323-36-6; 4528-51-2; 4528-52-3; 4530-70-5; 6W731X367Q
Scope Note: A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.
Terms: Selegiline Preferred Term
Term UI T037419
Date01/01/1999
LexicalTag NON
ThesaurusID; L-Deprenyl
Term UI T037418
Date09/20/1984
LexicalTag NON
ThesaurusID UNK (19XX); Selegyline
Term UI T037420
Date02/27/1991
LexicalTag NON
ThesaurusID NLM (1992); Selegiline, (R)-Isomer
Term UI T414325
Date05/15/2000
LexicalTag NON
ThesaurusID NLM (2001)

Deprenyl Narrower

Eldepryl Narrower

Selegiline Hydrochloride, (R,S)-Isomer Narrower

Selegiline Hydrochloride, (R)-Isomer Narrower

Selegiline, (S)-Isomer Related

Selegiline Hydrochloride, (S)-Isomer Narrower

Selegiline, (R,S)-Isomer Related

E-250 Narrower

Zelapar Narrower

Yumex Narrower

Emsam Narrower

Selegiline MeSH Descriptor Data 2024