MeSH Browser

MeSH Heading: Tetradecanoylphorbol Acetate
Tree Number(s): D02.455.849.291.500.510.850
Unique ID: D013755
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013755
Scope Note: A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
Entry Term(s): 12-Myristoyl-13-acetylphorbol; 12-O-Tetradecanoyl Phorbol 13-Acetate; Phorbol Myristate Acetate; Tetradecanoylphorbol Acetate, 4a alpha-Isomer
Pharm Action: Carcinogens
Related Numbers: 16561-29-8; 63597-44-4
CAS Type 1 Name: Tetradecanoic acid, 9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa(3,4)benz(1,2-e)azulen-9-yl ester, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-
Previous Indexing: Alcohols (1966-1974); Croton Oil (1966-1974); Diterpenes (1974); Fatty Acids (1966-1974); Terpenes (1966-1973)
Public MeSH Note: 87; was see under PHORBOLS 1975-86
History Note: 87(75); was see under PHORBOLS 1975-86
Date Established: 1987/01/01
Date of Entry: 1974/11/14
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0021224
Related Numbers: 16561-29-8; 63597-44-4
Scope Note: A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
Terms: Tetradecanoylphorbol Acetate Preferred Term
Term UI T040404
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); 12-Myristoyl-13-acetylphorbol
Term UI T040405
Date03/25/1991
LexicalTag NON
ThesaurusID NLM (1992); 12-O-Tetradecanoyl Phorbol 13-Acetate
Term UI T040402
Date03/18/1981
LexicalTag NON
ThesaurusID UNK (19XX); Phorbol Myristate Acetate
Term UI T040403
Date06/13/1983
LexicalTag NON
ThesaurusID

Tetradecanoylphorbol Acetate MeSH Descriptor Data 2024