MeSH Browser

MeSH Heading: omega-Agatoxin IVA
Tree Number(s): D12.644.400.562; D12.776.093.249.500; D20.888.065.870.324.500; D23.946.833.065.870.324.500
Unique ID: D020867
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020867
Scope Note: A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE.
Entry Term(s): omega-Aga-IVA
Pharm Action: Calcium Channel Blockers
Neurotoxins
Previous Indexing: Spider Venoms (1992-1999)
Public MeSH Note: 2000; OMEGA-AGATOXIN IVA was indexed under SPIDER VENOMS 1992-1999
History Note: 2000; use OMEGA-AGATOXIN IVA (NM) 1992-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/08
Revision Date: 2015/06/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

enzymology (EN)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

urine (UR)

omega-Agatoxin IVA MeSH Descriptor Data 2024