MeSH Browser

MeSH Heading: Pancreatic Polypeptide
Tree Number(s): D06.472.699.587.700; D12.644.400.600; D12.644.548.586.700; D12.776.631.650.600
Unique ID: D010191
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010191
Scope Note: A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
Entry Term(s): Pancreatic Polypeptide (PP); Pancreatic Polypeptide Hormone; Pancreatic Prohormone
Pharm Action: Gastrointestinal Agents
Hormones
Registry Numbers: 59763-91-6; 0
Previous Indexing: Hormones (1966-1973); Pancreatic Hormones (1974-1978); Peptides (1966-1978)
Public MeSH Note: 79
History Note: 79
Date Established: 1979/01/01
Date of Entry: 1978/05/18
Revision Date: 2015/11/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0015804
Registry Numbers: 59763-91-6
Scope Note: A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
Terms: Pancreatic Polypeptide Preferred Term
Term UI T030148
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); Pancreatic Polypeptide Hormone
Term UI T669766
Date03/28/2006
LexicalTag NON
ThesaurusID NLM (2007); Pancreatic Polypeptide (PP)
Term UI T669775
Date03/29/2006
LexicalTag NON
ThesaurusID NLM (2007)

Pancreatic Polypeptide MeSH Descriptor Data 2025