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Islets of Langerhans MeSH Descriptor Data 2025


MeSH Heading
Islets of Langerhans
Tree Number(s)
A03.734.414
A06.300.414
Unique ID
D007515
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007515
Annotation
do not confuse with LANGERHANS CELLS (skin); neoplasms = ADENOMA, ISLET CELL or CARCINOMA, ISLET CELL or their specifics
Scope Note
Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
Entry Term(s)
Islands of Langerhans
Islet Cells
Nesidioblasts
Pancreas, Endocrine
Pancreatic Islets
Public MeSH Note
91; was ISLANDS OF LANGERHANS 1963-90
Online Note
use ISLETS OF LANGERHANS to search ISLANDS OF LANGERHANS 1966-90
History Note
91; was ISLANDS OF LANGERHANS 1963-90
Entry Combination
transplantation:Islets of Langerhans Transplantation
Date Established
1991/01/01
Date of Entry
1999/01/01
Revision Date
2018/07/01
Islets of Langerhans Preferred
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