MeSH Browser

MeSH Supplementary: squalestatin 1
Unique ID: C075117
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C075117
Entry Term(s): 7-deoxy zaragozic acid; squalestatin; squalestatin s1; zaragozic acid A
Pharm Action: Anticholesteremic Agents
Antifungal Agents
Enzyme Inhibitors
Registry Number: 1117HVX02L
Related Numbers: 142561-96-4
CAS Type 1 Name: L-erythro-L-glycero-D-altro-7-trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-c-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-((2E,4S,6S)-4,6-dimethyl-2-octenoate), (7S)-
Previous Indexing: *BICYCLO COMPOUNDS (92-95)
Heading Mapped to: *Tricarboxylic Acids; *Bridged Bicyclo Compounds, Heterocyclic
Frequency: 99
Note: structure given in first source; inhibits both mammalian and fungal squalene synthetase; from fungus Phoma sp (Coelomycetes)
Source: J Biol Chem 1992 Jun 15;267(17):11705-8
Indexing Information: Farnesyl-Diphosphate Farnesyltransferase
Date of Entry: 1992/07/15
Revision Date: 2017/06/29

Concept UI: M0202501
Registry Number: 1117HVX02L
Related Numbers: 142561-96-4
Terms: squalestatin 1 Preferred Term
Term UI T232506
LexicalTag NON
ThesaurusID NLM (1992); squalestatin
Term UI T000928064
Date06/29/2017
LexicalTag NON
ThesaurusID NLM (2017); squalestatin s1
Term UI T000928065
Date06/29/2017
LexicalTag NON
ThesaurusID NLM (2017); zaragozic acid A
Term UI T232505
LexicalTag NON
ThesaurusID

squalestatin 1 MeSH Supplementary Concept Data 2024