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DAB(389)-interleukin 6 MeSH Supplementary Concept Data 2024


MeSH Supplementary
DAB(389)-interleukin 6
Unique ID
C081484
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C081484
Entry Term(s)
DAB(389)-IL6
Registry Number
0
Heading Mapped to
*Diphtheria Toxin
Recombinant Fusion Proteins
*Interleukin-6
Frequency
2
Note
MW 63.982 kDa; formed by the fusion of amino acids 1-184 of mature human IL-6 to Ala(389) of diphtheria toxin ; this toxin has been shown to bind to the IL-6 receptor; it is selectively cytotoxic for eukaryotic cells bearing the IL-6 receptor; has been sequenced
Source
Protein Eng 1993 Apr;6(3):305-11
Date of Entry
1993/06/30
Revision Date
2001/06/14
DAB(389)-interleukin 6 Preferred
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