MeSH Browser

MeSH Heading: Interleukin-6
Tree Number(s): D12.644.276.374.465.224; D12.776.467.374.465.202; D23.529.374.465.224
Unique ID: D015850
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015850
Scope Note: A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
Entry Term(s): B Cell Stimulatory Factor-2; B-Cell Differentiation Factor; B-Cell Differentiation Factor-2; B-Cell Stimulatory Factor 2; B-Cell Stimulatory Factor-2; BSF-2; Differentiation Factor, B-Cell; Differentiation Factor-2, B-Cell; Hepatocyte-Stimulating Factor; Hybridoma Growth Factor; IFN-beta 2; IL-6; IL6; Interferon beta-2; MGI-2; Myeloid Differentiation-Inducing Protein; Plasmacytoma Growth Factor
Previous Indexing: Interleukins (1988-1989); Lymphokines (1987)
See Also: Hybridomas; Plasmacytoma
Public MeSH Note: 90
History Note: 90
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2016/04/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intercellular Signaling Peptides and Proteins [D12.644.276]
    - Cytokines [D12.644.276.374]
      - Interleukins [D12.644.276.374.465]
        
        Interleukin-1 [D12.644.276.374.465.010]
        
        Interleukin-2 [D12.644.276.374.465.021]
        
        Interleukin-3 [D12.644.276.374.465.032]
        
        Interleukin-4 [D12.644.276.374.465.186]
        
        Interleukin-5 [D12.644.276.374.465.202]
        
        Interleukin-6 [D12.644.276.374.465.224]
        
        Interleukin-7 [D12.644.276.374.465.246]
        
        Interleukin-8 [D12.644.276.374.465.312]
        
        Interleukin-9 [D12.644.276.374.465.377]
        
        Interleukin-10 [D12.644.276.374.465.510]
        
        Interleukin-11 [D12.644.276.374.465.511]
        
        Interleukin-12 [D12.644.276.374.465.512]
        
        Interleukin-13 [D12.644.276.374.465.513]
        
        Interleukin-15 [D12.644.276.374.465.515]
        
        Interleukin-16 [D12.644.276.374.465.516]
        
        Interleukin-17 [D12.644.276.374.465.517]
        
        Interleukin-18 [D12.644.276.374.465.518]
        
        Interleukin-23 [D12.644.276.374.465.759]
        
        Interleukin-27 [D12.644.276.374.465.800]
        
        Interleukin-33 [D12.644.276.374.465.850]
        
        Interleukin-22 [D12.644.276.374.465.925]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Cytokines [D12.776.467.374]
      - Interleukins [D12.776.467.374.465]
        
        Interleukin-1 [D12.776.467.374.465.010]
        
        Interleukin-2 [D12.776.467.374.465.021]
        
        Interleukin-3 [D12.776.467.374.465.032]
        
        Interleukin-4 [D12.776.467.374.465.178]
        
        Interleukin-5 [D12.776.467.374.465.186]
        
        Interleukin-6 [D12.776.467.374.465.202]
        
        Interleukin-7 [D12.776.467.374.465.224]
        
        Interleukin-8 [D12.776.467.374.465.246]
        
        Interleukin-9 [D12.776.467.374.465.312]
        
        Interleukin-10 [D12.776.467.374.465.510]
        
        Interleukin-11 [D12.776.467.374.465.511]
        
        Interleukin-12 [D12.776.467.374.465.512]
        
        Interleukin-13 [D12.776.467.374.465.513]
        
        Interleukin-15 [D12.776.467.374.465.515]
        
        Interleukin-16 [D12.776.467.374.465.516]
        
        Interleukin-17 [D12.776.467.374.465.517]
        
        Interleukin-18 [D12.776.467.374.465.518]
        
        Interleukin-23 [D12.776.467.374.465.759]
        
        Interleukin-27 [D12.776.467.374.465.800]
        
        Interleukin-33 [D12.776.467.374.465.850]
        
        Interleukin-22 [D12.776.467.374.465.925]

Biological Factors [D23]
- Intercellular Signaling Peptides and Proteins [D23.529]
  - Cytokines [D23.529.374]
    - Interleukins [D23.529.374.465]

Interleukin-6 Preferred

Concept UI: M0024272
Scope Note: A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
Terms: Interleukin-6 Preferred Term
Term UI T047018
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); B Cell Stimulatory Factor-2
Term UI T047010
Date03/23/1989
LexicalTag NON
ThesaurusID NLM (1990); B-Cell Stimulatory Factor 2
Term UI T047011
Date03/23/1989
LexicalTag NON
ThesaurusID NLM (1990); B-Cell Stimulatory Factor-2
Term UI T047012
Date03/23/1989
LexicalTag NON
ThesaurusID NLM (1990); Differentiation Factor-2, B-Cell
Term UI T047013
Date03/05/1991
LexicalTag NON
ThesaurusID NLM (1992); B-Cell Differentiation Factor-2
Term UI T047014
Date03/23/1989
LexicalTag NON
ThesaurusID NLM (1990); BSF-2
Term UI T047015
Date03/23/1989
LexicalTag ABB
ThesaurusID NLM (1990); Hybridoma Growth Factor
Term UI T047016
Date03/23/1989
LexicalTag NON
ThesaurusID NLM (1990); IFN-beta 2
Term UI T047017
Date03/23/1989
LexicalTag ABB
ThesaurusID NLM (1990); Plasmacytoma Growth Factor
Term UI T047019
Date03/23/1989
LexicalTag NON
ThesaurusID NLM (1990); Hepatocyte-Stimulating Factor
Term UI T047020
Date03/30/1990
LexicalTag NON
ThesaurusID NLM (1991); MGI-2
Term UI T047021
Date03/20/1990
LexicalTag ABB
ThesaurusID NLM (1991); Myeloid Differentiation-Inducing Protein
Term UI T047022
Date03/20/1990
LexicalTag NON
ThesaurusID NLM (1991); B-Cell Differentiation Factor
Term UI T047023
Date03/05/1991
LexicalTag NON
ThesaurusID NLM (1992); Differentiation Factor, B-Cell
Term UI T047024
Date03/05/1991
LexicalTag NON
ThesaurusID NLM (1992); IL-6
Term UI T047025
Date05/25/1989
LexicalTag ABB
ThesaurusID NLM (1990); Interferon beta-2
Term UI T000888597
Date10/28/2015
LexicalTag NON
ThesaurusID NLM (2017); IL6
Term UI T047026
Date03/05/1991
LexicalTag ABB
ThesaurusID NLM (1992)

Interleukin-6 MeSH Descriptor Data 2024