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A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.
Entry Term(s)
IFN-gamma Inducing Factor
IFN-gamma-Inducing Factor
IL-18
IL18
Interferon-gamma Inducing Factor
Interferon-gamma-Inducing Factor
Registry Numbers
0
Previous Indexing
Cytokines (1995-1998)
Public MeSH Note
1999; INTERFERON-GAMMA INDUCING FACTOR (now INTERLEUKIN-18) was indexed under CYTOKINES 1995-1998
A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.