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T-Lymphocytes, Cytotoxic MeSH Descriptor Data 2022


MeSH Heading
T-Lymphocytes, Cytotoxic
Tree Number(s)
A11.118.637.555.283.875
A11.118.637.555.567.550.500.200
A11.118.637.555.567.569.220.200
A11.118.637.555.567.569.500.200
A15.145.229.637.555.283.875
A15.145.229.637.555.567.550.500.200
A15.145.229.637.555.567.569.220.200
A15.145.229.637.555.567.569.500.200
A15.382.490.555.283.875
A15.382.490.555.567.550.500.200
A15.382.490.555.567.569.220.200
A15.382.490.555.567.569.500.200
Unique ID
D013602
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013602
Annotation
if subpopulations are discussed, coordinate IM with T-LYMPHOCYTE SUBSETS (IM)
Scope Note
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.
Entry Version
T LYMPHOCYTES CYTOTOX
Entry Term(s)
Cell-Mediated Lympholytic Cells
Cytotoxic T Lymphocyte
Cytotoxic T-Lymphocytes
TC1 Cell
TC1 Cells
TC2 Cell
TC2 Cells
Previous Indexing
Cytotoxicity, Immunologic (1978-1982)
T Lymphocytes (1973-1982)
Public MeSH Note
90; was T LYMPHOCYTES, CYTOTOXIC 1983-89
Online Note
use T-LYMPHOCYTES, CYTOTOXIC to search T LYMPHOCYTES, CYTOTOXIC 1983-89
History Note
90; was T LYMPHOCYTES, CYTOTOXIC 1983-89
Date Established
1983/01/01
Date of Entry
1982/04/29
Revision Date
2020/05/27
T-Lymphocytes, Cytotoxic Preferred
TC2 Cells Narrower
TC1 Cells Narrower
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