MeSH Browser

MeSH Supplementary: FK506 macrolide 9-hydroxylase, Streptomyces
Unique ID: C101653
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C101653
Entry Term(s): FK520 macrolide 9-hydroxylase, Streptomyces; FkbD protein, Streptomyces; cytochrome P-450 9-deoxo-FK506 hydroxylase, Streptomyces
Registry Numbers: EC 1.14.-
Previous Indexing: *MIXED FUNCTION OXYGENASES (1996-2008)
Heading Mapped to: *Bacterial Proteins; *Cytochrome P-450 Enzyme System
Frequency: 2
Note: catalyzes hydroxylation at position C-9 of the FK506 and FK520 macrolactone ring; isolated from Streptomyces; FK506 and FK520 are 23-membered macrocyclic polyketides with potent immunosuppressive and antifungal activities
Source: J Bacteriol 1996 Sep;178(17):5243-8
Date of Entry: 1996/11/04
Revision Date: 2008/07/25

FK506 macrolide 9-hydroxylase, Streptomyces MeSH Supplementary Concept Data 2025