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ranirestat MeSH Supplementary Concept Data 2024


MeSH Supplementary
ranirestat
Unique ID
C115070
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C115070
Entry Term(s)
2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo(1,2-a)pyrazine-4-spiro-3'-pyrrolidine-1.2',3,5'-tetrone
AS 3201
AS-3201
SX 3030
SX 3202
SX-3030
SX-3202
Pharm Action
Enzyme Inhibitors
Registry Number
Z26P56GFTV
CAS Type 1 Name
Spiro(pyrrolidine-3,4'(1'H)-pyrrolo(1,2-a)pyrazine)-1',2,3',5(2'H)-tetrone, 2'-((4-bromo-2-fluorophenyl)methyl)-, (3R)-
Heading Mapped to
*Pyrazines
*Spiro Compounds
Frequency
30
Note
an aldose reductase inhibitor; AS-3201 and SX-3202 are the (R-(-))- and (S-(+))-isomers, respectively; structure in first source
Source
J Med Chem 1998 Oct 8;41(21):4118-29
Indexing Information
Aldehyde Reductase
Stereoisomerism
Date of Entry
1998/10/30
Revision Date
2017/08/24
ranirestat Preferred
SX 3030 Narrower
2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo(1,2-a)pyrazine-4-spiro-3'-pyrrolidine-1.2',3,5'-tetrone Broader
AS 3201 Narrower
SX 3202 Narrower
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